In Darwin’s Footsteps (Eastern Route)
9-day all-inclusive Galápagos expedition cruise from Quito to Guayaquil

Overview
9-day all-inclusive Galápagos expedition cruise from Quito to Guayaquil
Voyage Details
- Departs 21 Oct 2026
- Duration: 8 nights
- Region: GALAPAGOS
- Ship: MS Santa Cruz II
- Embarkation: Seymour
Expedition Highlights
- Flight in economy class from Quito to Baltra, and Baltra to Guayaquil, including all taxes
- Two hotel nights in Quito before the expedition cruise, including breakfast, and dinner on Day 2
- Transfers between the airport and the hotel in Quito before the expedition cruise
- Transfers between the airport and the ship in Baltra
- Full-day excursion: Historic Quito & Middle of the World, including lunch, before the expedition cruise
- Galápagos Islands National Park admission fee
- Transit control card for the Galápagos Islands
- Access to the airport lounge at the Guayaquil (or Quito) airport upon return from the Galápagos Islands for guests flying internationally on the day of disembarkation
Day-by-Day Itinerary
Day 1
Vibrant Quito

UIOAIR-HOT, UIO-JWM, ECUIO
Begin your adventure in the vibrant city of Quito Your journey begins on the Equator in the lush Andean foothills. At 9,350 feet, Quito is the second-highest capital city in the world, and its main draw is the exquisite Old Town which was founded on an ancient Inca settlement. A UNESCO World Heritage site, it’s packed with well-preserved colonial architecture as evidenced in colourful plazas, magnificent churches, and handsome monuments. Settle into your hotel and enjoy an overnight stay. If you have time, why not come a few days earlier and join one of our pre-voyage option.
Day 1
Vibrant Quito

UIOAIR-HOT, UIO-JWM, ECUIO
Begin your adventure in the vibrant city of Quito Your journey begins on the Equator in the lush Andean foothills. At 9,350 feet, Quito is the second-highest capital city in the world, and its main draw is the exquisite Old Town which was founded on an ancient Inca settlement. A UNESCO World Heritage site, it’s packed with well-preserved colonial architecture as evidenced in colourful plazas, magnificent churches, and handsome monuments. Settle into your hotel and enjoy an overnight stay. If you have time, why not come a few days earlier and join one of our pre-voyage option.
Day 2
Visit historic Quito

UIO-JWM, ECUIO
Straddle the Equator at the Middle of the World City Today you’ll enjoy a guided tour of Quito’s remarkable Old Town; it’s one of the largest and best-preserved colonial-era quarters in South America. Wander through cobblestone streets as you admire the architecture and sample some delicious chocolate made from finest Ecuadorian cacao along the way. Next, you’ll head to the iconic ‘Middle of the World City’, located around 16 miles north of Quito. After lunch, you’ll visit the famous monument that delineates the imaginary line of the Equator. Have your camera ready to capture the moment you stand with one foot in each hemisphere.
Day 2
Visit historic Quito

UIO-JWM, ECUIO
Straddle the Equator at the Middle of the World City Today you’ll enjoy a guided tour of Quito’s remarkable Old Town; it’s one of the largest and best-preserved colonial-era quarters in South America. Wander through cobblestone streets as you admire the architecture and sample some delicious chocolate made from finest Ecuadorian cacao along the way. Next, you’ll head to the iconic ‘Middle of the World City’, located around 16 miles north of Quito. After lunch, you’ll visit the famous monument that delineates the imaginary line of the Equator. Have your camera ready to capture the moment you stand with one foot in each hemisphere.
Day 3
Your cruise begins

UIOHOT-AIR, UIO, GPS
Get ready to explore the spectacular Galápagos Islands After breakfast, a short flight will take you to Baltra Island in the spectacular Galápagos archipelago. A transfer brings you straight to the port where your comfortable expedition ship MS Santa Cruz II awaits. You'll get your first glimpse of the islands' incredible wildlife on Mosquera Islet, home to one of the largest sea lion colonies in the archipelago. We'll take our small panga boats ashore to get a closer look. As you stroll across flat and sandy dunes, look out for blue-footed Boobies and Sally Lightfoot crabs, and learn about the marine and terrestrial ecosystems from your naturalist guides.
Day 3
Your cruise begins

UIOHOT-AIR, UIO, GPS
Get ready to explore the spectacular Galápagos Islands After breakfast, a short flight will take you to Baltra Island in the spectacular Galápagos archipelago. A transfer brings you straight to the port where your comfortable expedition ship MS Santa Cruz II awaits. You'll get your first glimpse of the islands' incredible wildlife on Mosquera Islet, home to one of the largest sea lion colonies in the archipelago. We'll take our small panga boats ashore to get a closer look. As you stroll across flat and sandy dunes, look out for blue-footed Boobies and Sally Lightfoot crabs, and learn about the marine and terrestrial ecosystems from your naturalist guides.
Day 4
San Cristóbal's tortoises

San Cristobal, EC
Meet the famous giant tortoises First our small expedition boats will take you to Punta Pitt, the only site in the Galápagos Islands where you might see three species of boobies. Enjoy a nature walk, explore the coastline by boat, or snorkel and swim in the crystal-clear water. Then we’ll head to the Cerro Colorado Tortoise Reserve – a breeding centre for the endangered giant tortoise. It's also home to other endemic species, including the San Cristobal Mockingbird and lava lizard. The giant tortoise is probably the most iconic of all Galápagos wildlife, with a lifespan of over 100 years. Here, they thrive, ambling around forests similar to their natural habitat.
Day 4
San Cristóbal's tortoises

San Cristobal, EC
Meet the famous giant tortoises First our small expedition boats will take you to Punta Pitt, the only site in the Galápagos Islands where you might see three species of boobies. Enjoy a nature walk, explore the coastline by boat, or snorkel and swim in the crystal-clear water. Then we’ll head to the Cerro Colorado Tortoise Reserve – a breeding centre for the endangered giant tortoise. It's also home to other endemic species, including the San Cristobal Mockingbird and lava lizard. The giant tortoise is probably the most iconic of all Galápagos wildlife, with a lifespan of over 100 years. Here, they thrive, ambling around forests similar to their natural habitat.
Day 5
Santa Fe and South Plaza

ECSN2, ECSP1
Spot wildlife against idyllic backdrops We start the day with a scenic nature walk on the blissful beaches of Santa Fe, home to the endemic Barrington land iguana and a colony of sea lions. You can swim or snorkel from our small panga boats, take a kayak for a paddle around the island, or join a trip in our glass-bottomed boat to observe the marine life below. After a delicious lunch, prepared by our onboard chefs, we head to South Plaza Island. Keep an eye out for frigatebirds, Swallow-tailed Gulls and Galapagos Shearwaters gliding on the breeze. Here, among a dazzling array of flora, land iguanas laze by the shore while marine iguanas slip in and out of the water.
Day 5
Santa Fe and South Plaza

ECSN2, ECSP1
Spot wildlife against idyllic backdrops We start the day with a scenic nature walk on the blissful beaches of Santa Fe, home to the endemic Barrington land iguana and a colony of sea lions. You can swim or snorkel from our small panga boats, take a kayak for a paddle around the island, or join a trip in our glass-bottomed boat to observe the marine life below. After a delicious lunch, prepared by our onboard chefs, we head to South Plaza Island. Keep an eye out for frigatebirds, Swallow-tailed Gulls and Galapagos Shearwaters gliding on the breeze. Here, among a dazzling array of flora, land iguanas laze by the shore while marine iguanas slip in and out of the water.
Day 6
Darwin’s Santa Cruz

ECAYO, ECCD1
Meet the famous giant tortoises of Galápagos Today, you’ll explore Santa Cruz Island. In the morning, we’ll disembark at Puerto Ayora to visit the Charles Darwin Research Station. A giant tortoise breeding centre, here you can see recently hatched tortoises and Darwin’s famous finches: the birds he used as a basis for his theory of evolution by natural selection. There’s also an impressive forest of prickly pear cacti that’s home to many land birds. Enjoy a cooler climate over lunch in the lush highlands, where giant tortoises shuffle about munching on grass and wallowing in pools. You'll have time for another activity, including mountain biking or visiting a sugar plantation.
Day 6
Darwin’s Santa Cruz

ECAYO, ECCD1
Meet the famous giant tortoises of Galápagos Today, you’ll explore Santa Cruz Island. In the morning, we’ll disembark at Puerto Ayora to visit the Charles Darwin Research Station. A giant tortoise breeding centre, here you can see recently hatched tortoises and Darwin’s famous finches: the birds he used as a basis for his theory of evolution by natural selection. There’s also an impressive forest of prickly pear cacti that’s home to many land birds. Enjoy a cooler climate over lunch in the lush highlands, where giant tortoises shuffle about munching on grass and wallowing in pools. You'll have time for another activity, including mountain biking or visiting a sugar plantation.
Day 7
Dramatic Española

ECAYO, ECCD1
Lava lizards and incredible birdlife Your Galápagos Islands cruise reaches Española, the archipelago's most southerly island. Birdlife here is truly extraordinary. Look out for Nazca boobies, blue-footed boobies and swallow-tailed gulls, and the mighty waved albatross on cruises April through December. It’s also a chance to spot red Española lava lizards and marine iguanas, as well as see the famous blowhole, El Soplador, blasting water 75 feet into the air. After lunch on board the ship, we'll head to the picturesque coral beach of Gardner Bay and nearby Osborn Islet, to seek out sea lions, mockingbirds, and finches. If you're feeling active, you can go snorkelling or kayaking.
Day 7
Dramatic Española

ECAYO, ECCD1
Lava lizards and incredible birdlife Your Galápagos Islands cruise reaches Española, the archipelago's most southerly island. Birdlife here is truly extraordinary. Look out for Nazca boobies, blue-footed boobies and swallow-tailed gulls, and the mighty waved albatross on cruises April through December. It’s also a chance to spot red Española lava lizards and marine iguanas, as well as see the famous blowhole, El Soplador, blasting water 75 feet into the air. After lunch on board the ship, we'll head to the picturesque coral beach of Gardner Bay and nearby Osborn Islet, to seek out sea lions, mockingbirds, and finches. If you're feeling active, you can go snorkelling or kayaking.
Day 8
Reef life on Eden Islet

ECEI1, ECSM1
Green turtles, sharks and rare bird colonies The wealth of wildlife watching opportunities continues at Eden Islet, where we hope to see Galapagos green turtles, rays, and friendly reef sharks. On the shore, look out for distinctive frigatebirds with their rubbery, red throats. You can swim or snorkel to explore the reefs. Alternatively, see the reefs from our glass-bottomed boat or by kayak. After lunch, we'll sail to North Seymour. The island is a great site for spotting colonies of blue-footed boobies and Swallow-tailed Gulls. Sea lions and marine iguanas also congregate here, attracted by the bountiful sea life in its waters.
Day 8
Reef life on Eden Islet

ECEI1, ECSM1
Green turtles, sharks and rare bird colonies The wealth of wildlife watching opportunities continues at Eden Islet, where we hope to see Galapagos green turtles, rays, and friendly reef sharks. On the shore, look out for distinctive frigatebirds with their rubbery, red throats. You can swim or snorkel to explore the reefs. Alternatively, see the reefs from our glass-bottomed boat or by kayak. After lunch, we'll sail to North Seymour. The island is a great site for spotting colonies of blue-footed boobies and Swallow-tailed Gulls. Sea lions and marine iguanas also congregate here, attracted by the bountiful sea life in its waters.
Day 9
End of your expedition

GPS, UIO
From the Galápagos Islands to Guayaquil Your expedition cruise draws to a close as you disembark at Baltra Island. A transfer will take you to the airport in Baltra for your flight to Guayaquil (or if you prefer, to Quito) to connect to your international flight. To explore more of Ecuador, why not extend your stay and join one of our post-voyage options. As you leave this fascinating region, you'll take with you incredible memories of amazing wildlife and wonderful experiences few have the privilege of seeing.
Day 9
End of your expedition

GPS, UIO
From the Galápagos Islands to Guayaquil Your expedition cruise draws to a close as you disembark at Baltra Island. A transfer will take you to the airport in Baltra for your flight to Guayaquil (or if you prefer, to Quito) to connect to your international flight. To explore more of Ecuador, why not extend your stay and join one of our post-voyage options. As you leave this fascinating region, you'll take with you incredible memories of amazing wildlife and wonderful experiences few have the privilege of seeing.
Gallery






Your Ship

MS Santa Cruz II
When exploring the Galápagos islands with us onboard the MS Santa Cruz II, guests will enjoy a relaxed atmosphere in high quality surroundings. The relatively small size - with a guest capacity of maximum of 90 allows for a cozy yet classy environment. Your clients will easily feel at home onboard.
- Built
- 2007
- Guests
- 200
- Gross tonnage
- 11,647 t
- Length
- 114 m
Pricing & Booking
Prices are per person in AUD on a double-occupancy basis. Contact us to confirm availability and current offers for this sailing.
Typically included
- Flight in economy class from Quito to Baltra, and Baltra to Guayaquil, including all taxes
- Two hotel nights in Quito before the expedition cruise, including breakfast, and dinner on Day 2
- Transfers between the airport and the hotel in Quito before the expedition cruise
- Transfers between the airport and the ship in Baltra
- Full-day excursion: Historic Quito & Middle of the World, including lunch, before the expedition cruise
- Galápagos Islands National Park admission fee
Cabin Grades
DS | Darwin Suite
Up to 3 guests · Single AUD 23,694
From AUD 12,932pp
EE | Explorer cabin
Up to 2 guests · Single AUD 15,117
From AUD 10,760pp
EH | Explorer cabin
Up to 2 guests · Single AUD 14,305
From AUD 10,218pp
EP | Explorer cabin
Up to 2 guests · Single AUD 15,929
From AUD 11,301pp
FH | Explorer family cabin
Up to 3 guests · Single AUD 15,929
From AUD 11,301pp
Unspecified cabin for 2 people
Up to 2 guests · Single AUD 26,640
From AUD 18,596pp
VH | Voyager cabin
Single occupancy · Single AUD 12,332
From AUD 12,113pp
Ready to explore with HX Expeditions?
From AUD 10,218 per person. Speak to a CruiseLiaise expedition specialist.